Gremlin Regulates Tubular Epithelial to Mesenchymal Transition via VEGFR2: Potential Role in Renal Fibrosis

• Main Authors: Laura Marquez-Exposito (Author), Carolina Lavoz (Author), Raul R. Rodrigues-Diez (Author), Sandra Rayego-Mateos (Author), Macarena Orejudo (Author), Elena Cantero-Navarro (Author), Alberto Ortiz (Author), Jesús Egido (Author), Rafael Selgas (Author), Sergio Mezzano (Author), Marta Ruiz-Ortega (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic kidney disease (CKD) is emerging as an important health problem due to the increase number of CKD patients and the absence of an effective curative treatment. Gremlin has been proposed as a novel therapeutic target for renal inflammatory diseases, acting via Vascular Endothelial Growth Facto...