Biodegradable calcium sulfide-based nanomodulators for H2S-boosted Ca2+-involved synergistic cascade cancer therapy

• Main Authors: Chuchu Lin (Author), Chenyi Huang (Author), Zhaoqing Shi (Author), Meitong Ou (Author), Shengjie Sun (Author), Mian Yu (Author), Ting Chen (Author), Yunfei Yi (Author), Xiaoyuan Ji (Author), Feng Lv (Author), Meiying Wu (Author), Lin Mei (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hydrogen sulfide (H2S) is the most recently discovered gasotransmitter molecule that activates multiple intracellular signaling pathways and exerts concentration-dependent antitumor effect by interfering with mitochondrial respiration and inhibiting cellular ATP generation. Inspired by the fact that...