Supersaturation and Solubilization upon In Vitro Digestion of Fenofibrate Type I Lipid Formulations: Effect of Droplet Size, Surfactant Concentration and Lipid Type

• প্রধান লেখক: Vladimir Katev (Author), Sonya Tsibranska-Gyoreva (Author), Zahari Vinarov (Author), Slavka Tcholakova (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2021-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Lipid-based formulations (LBF) enhance oral drug absorption by promoting drug solubilization and supersaturation. The aim of the study was to determine the effect of the lipid carrier type, drop size and surfactant concentration on the rate of fenofibrate release in a bicarbonate-based in vitro dige...