1H NMR-based serum metabolomics reveals erythromycin-induced liver toxicity in albino Wistar rats

• Main Authors: Atul Rawat (Author), Durgesh Dubey (Author), Anupam Guleria (Author), Umesh Kumar (Author), Amit K Keshari (Author), Swati Chaturvedi (Author), Anand Prakash (Author), Sudipta Saha (Author), Dinesh Kumar (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Erythromycin (ERY) is known to induce hepatic toxicity which mimics other liver diseases. Thus, ERY is often used to produce experimental models of drug-induced liver-toxicity. The serum metabolic profiles can be used to evaluate the liver-toxicity and to further improve the understand...