Delayed Type Allergic Itch-Associated Response Induced by Toluene-2,4-diisocyanate in Hairless Mice

• Váldodahkkit: Kazuhiro Fuchibe (Dahkki), Takeshi Nabe (Dahkki), Masanori Fujii (Dahkki), Nobuaki Mizutani (Dahkki), Kiichiro Danno (Dahkki), Akihide Koda (Dahkki), Shigekatsu Kohno (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2003-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

ABSTRACT: To develop an allergic dermatitis model showing persistent scratching in mice, toluene-2,4-diisocyanate (TDI) was repeatedly painted onto the skin of hairless HR-1 mice, and induction of itch-associated scratching behavior was observed. When HR-1 mice were epicutaneously sensitized with 1%...