The association of ARRB1 polymorphisms with response to antidepressant treatment in depressed patients

• Main Authors: Kenneth Chappell (Author), Abd El Kader Ait Tayeb (Author), Romain Colle (Author), Jérôme Bouligand (Author), Khalil El-Asmar (Author), Florence Gressier (Author), Séverine Trabado (Author), Denis Joseph David (Author), Bruno Feve (Author), Laurent Becquemont (Author), Emmanuelle Corruble (Author), Céline Verstuyft (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: β-arrestin 1, a protein encoded by ARRB1 involved in receptor signaling, is a potential biomarker for the response to antidepressant drug (ATD) treatment in depression. We examined ARRB1 genetic variants for their association with response following ATD treatment in METADAP, a cohort o...