Accurate detection of KRAS, NRAS and BRAF mutations in metastatic colorectal cancers by bridged nucleic acid-clamp real-time PCR
Abstract Background Patients with metastatic colorectal cancer can benefit from anti-EGFR therapy, such as cetuximab and panitumumab. However, colorectal cancers harboring constitutive activating mutations in KRAS, NRAS and BRAF genes are not responsive to anti-EGFR therapy. To select patients for a...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
BMC,
2019-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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