Medications Modulating the Acid Sphingomyelinase/Ceramide System and 28-Day Mortality among Patients with SARS-CoV-2: An Observational Study

• Main Authors: Nicolas Hoertel (Author), Katayoun Rezaei (Author), Marina Sánchez-Rico (Author), Alfonso Delgado-Álvarez (Author), Johannes Kornhuber (Author), Erich Gulbins (Author), Mark Olfson (Author), Charles Ouazana-Vedrines (Author), Alexander Carpinteiro (Author), Céline Cougoule (Author), Katrin Anne Becker (Author), Jesús M. Alvarado (Author), Frédéric Limosin (Author), on behalf of the AP-HP/Université Paris Cité/INSERM (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prior evidence indicates the potential central role of the acid sphingomyelinase (ASM)/ceramide system in the infection of cells with SARS-CoV-2. We conducted a multicenter retrospective observational study including 72,105 adult patients with laboratory-confirmed SARS-CoV-2 infection who were admit...