Aldo keto reductases 1B in endocrinology and metabolism

• 主要な著者: Emilie ePastel (著者), Jean-Christophe ePointud (著者), Fanny eVolat (著者), Antoine eMartinez (著者), Anne-Marie eLefr (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2012-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The aldose reductase (human AKR1B1/mouse Akr1b3) has been the focus of many research because of its role in diabetic complications. The starting point of these alterations is the massive entry of glucose in polyol pathway where it is converted into sorbitol by this enzyme. However, the issue of aldo...