Characterization of serum anti-diphtheria antibody activity following administration of equine anti-toxin for suspected diphtheria

• Main Authors: Heidi L. Smith (Author), Greg Saia (Author), Maria Lobikin (Author), Tejpratap Tiwari (Author), Su-Chun Cheng (Author), Deborah C. Molrine (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is a global shortage of equine-derived diphtheria anti-toxin (DAT) for diphtheria treatment. There are few existing data on serum antibody concentrations and neutralizing activity post-treatment to support development of new therapeutics. Antibody concentrations were quantified by ELISA and an...