Reproductive status of Onchocerca volvulus after ivermectin treatment in an ivermectin-naïve and a frequently treated population from Cameroon.

• Main Authors: Hugues C Nana-Djeunga (Author), Catherine Bourguinat (Author), Sébastien D Pion (Author), Jean Bopda (Author), Jonas A Kengne-Ouafo (Author), Flobert Njiokou (Author), Roger K Prichard (Author), Samuel Wanji (Author), Joseph Kamgno (Author), Michel Boussinesq (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

For two decades, onchocerciasis control has been based on mass treatment with ivermectin (IVM), repeated annually or six-monthly. This drug kills Onchocerca volvulus microfilariae (mf) present in the skin and the eyes (microfilaricidal effect) and prevents for 3-4 months the release of new mf by adu...