Evaluating Low HER2 Status in Invasive Breast Carcinoma via HER2 Immunohistochemistry, with HER2 FISH Correlation: A Cohort of 112 Patients

• Main Authors: Gokce Deniz Ardor (Author), Miglena K. Komforti (Author), Helena Hanna (Author), Onur Ibanoglu (Author), Abigail Lochala (Author), Aziza Nassar (Author)
• Format: Book
• Published: Hindawi-Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Recent trials demonstrated clinically significant benefits in HER2-nonamplified breast cancer with HER2-low expression using novel anti-HER2 antibody-drug conjugates. Thus, HER2-low breast cancer was proposed as a separate diagnostic entity. Herein, we reclassify HER2-negative cancers...