Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome

• Main Authors: Zhilei Wang (Author), Guang Xu (Author), Yuan Gao (Author), Xiaoyan Zhan (Author), Nan Qin (Author), Shubin Fu (Author), Ruisheng Li (Author), Ming Niu (Author), Jiabo Wang (Author), Youping Liu (Author), Xiaohe Xiao (Author), Zhaofang Bai (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aberrant activation of NLRP3 inflammasome has been implicated in the pathogenesis of diverse inflammation-related diseases, and pharmacological molecules targeting NLRP3 inflammasome are of considerable value to identifying potential therapeutic interventions. Cardamonin (CDN), the major active ingr...