Circulating plasma microRNA profiling in patients with polymyositis/dermatomyositis before and after treatment: miRNA may be associated with polymyositis/dermatomyositis

• Main Authors: Takuya Hirai (Author), Keigo Ikeda (Author), Hiroshi Tsushima (Author), Maki Fujishiro (Author), Kunihiro Hayakawa (Author), Yuko Yoshida (Author), Shinji Morimoto (Author), Ken Yamaji (Author), Yoshinari Takasaki (Author), Kenji Takamori (Author), Naoto Tamura (Author), Iwao Sekigawa (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background MicroRNAs (miRNAs) are involved in the regulation of key biological processes and have been implicated in various diseases, including autoimmune disorders. The pathogenesis of polymyositis (PM) and dermatomyositis (DM) is considered to be mediated by autoimmune reactions. To dete...