Neuromedin B Induces Acute Itch in Mice via the Activation of Peripheral Sensory Neurons

• Egile Nagusiak: Sarah Ehling (Egilea), Tomoki Fukuyama (Egilea), Mei-Chuan Ko (Egilea), Thierry Olivry (Egilea), Wolfgang Bäumer (Egilea)
• Formatua: Liburua
• Argitaratua: Medical Journals Sweden, 2019-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Neuromedin B is expressed in nociceptive and itch-sensitive dorsal root ganglia neurons, but its peripheral pruritogenic potential is not well described. The potential of neuromedin B as a pruritogen and pro-inflammatory peptide in the skin was tested in vivo in an acute model in mice and monkeys as...