IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers.

• المؤلفون الرئيسيون: Tatiane Assone (مؤلف), Fernando Vieira de Souza (مؤلف), Karen Oliveira Gaester (مؤلف), Luiz Augusto Marcondes Fonseca (مؤلف), Olinda do Carmo Luiz (مؤلف), Fernanda Malta (مؤلف), João Renato Rebello Pinho (مؤلف), Fernanda de Toledo Gonçalves (مؤلف), Alberto Jose da Silva Duarte (مؤلف), Augusto Cesar Penalva de Oliveira (مؤلف), Jorge Casseb (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

BACKGROUND:The polymorphisms of IL28B have been described as important in the pathogenesis of infections caused by some viruses. The aim of this research was to evaluate whether IL28B gene polymorphisms (SNP rs8099917 and SNP rs12979860) are associated with HAM/TSP. METHODS:The study included 229 su...