IL28B gene polymorphism SNP rs8099917 genotype GG is associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in HTLV-1 carriers.

• Main Authors: Tatiane Assone (Author), Fernando Vieira de Souza (Author), Karen Oliveira Gaester (Author), Luiz Augusto Marcondes Fonseca (Author), Olinda do Carmo Luiz (Author), Fernanda Malta (Author), João Renato Rebello Pinho (Author), Fernanda de Toledo Gonçalves (Author), Alberto Jose da Silva Duarte (Author), Augusto Cesar Penalva de Oliveira (Author), Jorge Casseb (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The polymorphisms of IL28B have been described as important in the pathogenesis of infections caused by some viruses. The aim of this research was to evaluate whether IL28B gene polymorphisms (SNP rs8099917 and SNP rs12979860) are associated with HAM/TSP. METHODS:The study included 229 su...