Lirioresinol B dimethyl ether inhibits NF-κB and COX-2 and activates IκBα expression in CCl4-induced hepatic fibrosis

• Main Authors: Adeeb Shehzad (Author), Shagufta Rehmat (Author), Salman Ul-Islam (Author), Rizwan Ahmad (Author), Meneerah Aljafary (Author), Noor A. Alrushaid (Author), Ebtesam A. Al-Suhaimi (Author)
• Format: Book
• Published: BMC, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Inflammation is one of the key components in the initiation and progression of hepatic diseases. If not treated, inflammation may cause cell dysplasia, and ultimately cancer. In the current study, we investigated the anti-inflammatory and anti-cancer activities of plant isolated...