SOST/Sclerostin impairs the osteogenesis and angiogesis in glucocorticoid-associated osteonecrosis of femoral head

• Main Authors: Junming Huang (Author), Tianle Ma (Author), Chenzhong Wang (Author), Zhe Wang (Author), Xinyuan Wang (Author), Bingxuan Hua (Author), Chang Jiang (Author), Zuoqin Yan (Author)
• Format: Book
• Published: BMC, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Glucocorticoid-associated osteonecrosis of the femoral head (GA-ONFH) is a progressive bone disorder which frequently results in femoral head collapse and hip joint dysfunction. Sclerostin (SOST) is principally secreted by osteocytes in bone and plays an important role in bone ho...