Control of HCV Replication With iMIRs, a Novel Anti-RNAi Agent

• Main Authors: Saori Itami (Author), Yutaka Eguchi (Author), Takayuki Mizutani (Author), Eriko Aoki (Author), Tadaaki Ohgi (Author), Masahiko Kuroda (Author), Takahiro Ochiya (Author), Nobuyuki Kato (Author), Hiroshi I Suzuki (Author), Norifumi Kawada (Author), Yoshiki Murakami (Author)
• Format: Book
• Published: Elsevier, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

MicroRNAs (miRNAs) serve important roles in regulating various physiological activities through RNA interference (RNAi). miR-122 is an important mediator of RNAi that is known to control hepatitis C virus (HCV) replication and is being investigated in clinical trials as a target for anti-HCV therapy...