Targeting ulcerative colitis by suppressing glucose uptake with ritonavir

• Hoofdauteurs: Henrika Jodeleit (Auteur), Omar Al-Amodi (Auteur), Janina Caesar (Auteur), Christina Villarroel Aguilera (Auteur), Lesca Holdt (Auteur), Roswitha Gropp (Auteur), Florian Beigel (Auteur), Matthias Siebeck (Auteur)
• Formaat: Boek
• Gepubliceerd in: The Company of Biologists, 2018-11-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Glucose is the preferred source of energy in activated inflammatory cells. Glucose uptake into the cell is ensured by a family of glucose uptake transporters (GLUTs), which have been identified as off-target molecules of the HIV protease inhibitor ritonavir. In this study, we examined the effect of...