Gefitinib loaded nanostructured lipid carriers: characterization, evaluation and anti-human colon cancer activity in vitro

• Main Authors: Hafiz A. Makeen (Author), Syam Mohan (Author), Mohamed Ahmed Al-Kasim (Author), Ibraheem M. Attafi (Author), Rayan A. Ahmed (Author), Nabeel Kashan Syed (Author), Muhammad Hadi Sultan (Author), Mohammed Al-Bratty (Author), Hassan A. Alhazmi (Author), Mohammed M. Safhi (Author), Raisuddin Ali (Author), M. Intakhab Alam (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

NLC containing Gefitinib (NANOGEF) was prepared using stearic acid, sesame oil and surfactants (sodium lauryl sulfate and tween 80). NANOGEFs were evaluated for particle size, polydispersity index (PdI), zeta potential, entrapment efficiency (EE), stability, release studies and cytotoxicity studies...