TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

• मुख्य लेखकों: Yue-Meng Wan (लेखक), Hua-Mei Wu (लेखक), Yu-Hua Li (लेखक), Zhi-Yuan Xu (लेखक), Jin-Hui Yang (लेखक), Chang Liu (लेखक), Yue-Feng He (लेखक), Men-Jie Wang (लेखक), Xi-Nan Wu (लेखक), Yuan Zhang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Tumor necrosis factor (TNF)-α-stimulated protein 6 (TSG-6) is a secreted protein with diverse tissue protective and anti-inflammatory properties. We aimed to investigate its effects in treating mice with alcoholic hepatitis (AH) and the associated mechanisms. AH was induced in 8-10 week female C57BL...