TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

• Päätekijät: Yue-Meng Wan (Tekijä), Hua-Mei Wu (Tekijä), Yu-Hua Li (Tekijä), Zhi-Yuan Xu (Tekijä), Jin-Hui Yang (Tekijä), Chang Liu (Tekijä), Yue-Feng He (Tekijä), Men-Jie Wang (Tekijä), Xi-Nan Wu (Tekijä), Yuan Zhang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Tumor necrosis factor (TNF)-α-stimulated protein 6 (TSG-6) is a secreted protein with diverse tissue protective and anti-inflammatory properties. We aimed to investigate its effects in treating mice with alcoholic hepatitis (AH) and the associated mechanisms. AH was induced in 8-10 week female C57BL...