TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation

• Hauptverfasser: Yue-Meng Wan (Verfasst von), Hua-Mei Wu (Verfasst von), Yu-Hua Li (Verfasst von), Zhi-Yuan Xu (Verfasst von), Jin-Hui Yang (Verfasst von), Chang Liu (Verfasst von), Yue-Feng He (Verfasst von), Men-Jie Wang (Verfasst von), Xi-Nan Wu (Verfasst von), Yuan Zhang (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Tumor necrosis factor (TNF)-α-stimulated protein 6 (TSG-6) is a secreted protein with diverse tissue protective and anti-inflammatory properties. We aimed to investigate its effects in treating mice with alcoholic hepatitis (AH) and the associated mechanisms. AH was induced in 8-10 week female C57BL...