GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition

• Auteurs principaux: Xiao-Ming Zhou (Auteur), Gui-Liang Wang (Auteur), Xiao-Bo Wang (Auteur), Li Liu (Auteur), Qin Zhang (Auteur), Yan Yin (Auteur), Qiu-Yue Wang (Auteur), Jian Kang (Auteur), Gang Hou (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Objective: Idiopathic pulmonary fibrosis is an irreversible and progressive fibrotic lung disease that leads to declines in pulmonary function and, eventually, respiratory failure and has no effective treatment. Gly-His-Lys (GHK) is a tripeptide involved in the processes of tissue regeneration and w...