Lignosulfonic Acid Sodium Is a Noncompetitive Inhibitor of Human Factor XIa

• Main Authors: Srabani Kar (Author), Page Bankston (Author), Daniel K. Afosah (Author), Rami A. Al-Horani (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2021-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The anticoagulant activity of lignosulfonic acid sodium (LSAS), a non-saccharide heparin mimetic, was investigated in this study. LSAS is a relatively safe industrial byproduct with similar polyanionic characteristics to that of heparin. Human plasma clotting assays, fibrin polymerization testing, a...