Demonstration of the Early Cardiac Bioavailability of a Non-Specific Cell-Targeted Peptide Using Radionuclide-Based Imaging In Vivo

• Үндсэн зохиолчид: Stephan Settelmeier (Зохиогч), Zohreh Varasteh (Зохиогч), Magdalena Staniszewska (Зохиогч), Anna-Lena Beerlage (Зохиогч), Fadi Zarrad (Зохиогч), Wolfgang P. Fendler (Зохиогч), Christoph Rischpler (Зохиогч), Johannes Notni (Зохиогч), Matthias Totzeck (Зохиогч), Ken Herrmann (Зохиогч), Tienush Rassaf (Зохиогч), Ulrike B. Hendgen-Cotta (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The cardiac bioavailability of peptide drugs that inhibit harmful intracellular protein-protein interactions in cardiovascular diseases remains a challenging task in drug development. This study investigates whether a non-specific cell-targeted peptide drug is available in a timely manner at its int...