Demonstration of the Early Cardiac Bioavailability of a Non-Specific Cell-Targeted Peptide Using Radionuclide-Based Imaging In Vivo

• Päätekijät: Stephan Settelmeier (Tekijä), Zohreh Varasteh (Tekijä), Magdalena Staniszewska (Tekijä), Anna-Lena Beerlage (Tekijä), Fadi Zarrad (Tekijä), Wolfgang P. Fendler (Tekijä), Christoph Rischpler (Tekijä), Johannes Notni (Tekijä), Matthias Totzeck (Tekijä), Ken Herrmann (Tekijä), Tienush Rassaf (Tekijä), Ulrike B. Hendgen-Cotta (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-05-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The cardiac bioavailability of peptide drugs that inhibit harmful intracellular protein-protein interactions in cardiovascular diseases remains a challenging task in drug development. This study investigates whether a non-specific cell-targeted peptide drug is available in a timely manner at its int...