MMP-9 as a Candidate Marker of Response to BRAF Inhibitors in Melanoma Patients With BRAFV600E Mutation Detected in Circulating-Free DNA

• Main Authors: Rossella Salemi (Author), Luca Falzone (Author), Gabriele Madonna (Author), Jerry Polesel (Author), Diana Cinà (Author), Domenico Mallardo (Author), Paolo A. Ascierto (Author), Massimo Libra (Author), Saverio Candido (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The BRAFV600E mutation is associated with melanoma development and its detection in circulating-free DNA cannot be observed in all melanoma patients harboring this mutation in tumor specimens. Beside the circulating-free DNA BRAFV600E mutation, other markers of therapeutic response should be identif...