Neutralizing Carbapenem Resistance by Co-Administering Meropenem with Novel β-Lactam-Metallo-β-Lactamase Inhibitors

• Main Authors: Nakita Reddy (Author), Letisha Girdhari (Author), Mbongeni Shungube (Author), Arnoldus C. Gouws (Author), Byron K. Peters (Author), Kamal K. Rajbongshi (Author), Sooraj Baijnath (Author), Sipho Mdanda (Author), Thandokuhle Ntombela (Author), Thilona Arumugam (Author), Linda A. Bester (Author), Sanil D. Singh (Author), Anil Chuturgoon (Author), Per I. Arvidsson (Author), Glenn E. M Maguire (Author), Hendrik G. Kruger (Author), Thavendran Govender (Author), Tricia Naicker (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Virulent Enterobacterale strains expressing serine and metallo-β-lactamases (MBL) genes have emerged responsible for conferring resistance to hard-to-treat infectious diseases. One strategy that exists is to develop β-lactamase inhibitors to counter this resistance. Currently, serine β-lactamase inh...