Activation of A2A Receptor by PDRN Reduces Neuronal Damage and Stimulates WNT/β-CATENIN Driven Neurogenesis in Spinal Cord Injury

• Main Authors: Natasha Irrera (Author), Vincenzo Arcoraci (Author), Federica Mannino (Author), Giovanna Vermiglio (Author), Giovanni Pallio (Author), Letteria Minutoli (Author), Gianluca Bagnato (Author), Giuseppe Pio Anastasi (Author), Emanuela Mazzon (Author), Placido Bramanti (Author), Francesco Squadrito (Author), Domenica Altavilla (Author), Alessandra Bitto (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Spinal cord injury (SCI) is a complex clinical and progressive condition characterized by neuronal loss, axonal destruction and demyelination. In the last few years, adenosine receptors have been studied as a target for many diseases, including neurodegenerative conditions. The aim of this study was...