In Vitro Cytotoxicity and In Vivo Antitumor Activity of Lipid Nanocapsules Loaded with Novel Pyridine Derivatives

• Päätekijät: Amr Selim Abu Lila (Tekijä), Mohammed Amran (Tekijä), Mohamed A. Tantawy (Tekijä), Ehssan H. Moglad (Tekijä), Shadeed Gad (Tekijä), Hadil Faris Alotaibi (Tekijä), Ahmad J. Obaidullah (Tekijä), El-Sayed Khafagy (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2023-06-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

This study demonstrates high drug-loading of novel pyridine derivatives (S1-S4) in lipid- and polymer-based core-shell nanocapsules (LPNCs) for boosting the anticancer efficiency and alleviating toxicity of these novel pyridine derivatives. The nanocapsules were fabricated using a nanoprecipitation...