A new methodology for polyvalent intravenous immunoglobulin solution production with a two-stage process of viral inactivation

• Main Authors: Antônio Edson de Souza Lucena (Author), Divaldo de Almeida Sampaio (Author), Ednaldo Rosas da Silva (Author), Virgínia Florêncio de Paiva (Author), Ana Cláudia Santiago (Author), Ana Cristina Lima Leite (Author)
• Format: Book
• Published: Universidade de São Paulo, 2010-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Highly purified intravenous immunoglobulin G concentrate (IV IgG) was produced with the use of polyethylene glycol associated to a single-stage precipitation by ethanol, instead of the classic Cohn-Oncley process, which employs cold alcohol as the precipitating agent, in a three-stage process. Preci...