Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

Background: Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, and atazanavir (ATV), a protease inhibitor, are drugs widely used in antiretroviral therapy (ART) for people living with HIV. These drugs have shown high interindividual variability in adverse drug reactions (ADRs). UGT1A...

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Main Authors: Daniela Poblete (Author), Fernando Bernal (Author), Gabriel Llull (Author), Sebastian Archiles (Author), Patricia Vasquez (Author), Leonardo Chanqueo (Author), Nicole Soto (Author), María A. Lavanderos (Author), Luis A. Quiñones (Author), Nelson M. Varela (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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