Multi-Dose Intravenous Administration of Neutral and Cationic Liposomes in Mice: An Extensive Toxicity Study

• मुख्य लेखकों: Stéphanie Andrade (लेखक), Joana A. Loureiro (लेखक), Santiago Ramirez (लेखक), Celso S. G. Catumbela (लेखक), Claudio Soto (लेखक), Rodrigo Morales (लेखक), Maria Carmo Pereira (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Liposomes are widely used as delivery systems for therapeutic purposes. However, the toxicity associated with the multi-dose administration of these nanoparticles is not fully elucidated. Here, we evaluated the toxicity of the prolonged administration of liposomes composed of neutral or cationic pho...