Multi-Dose Intravenous Administration of Neutral and Cationic Liposomes in Mice: An Extensive Toxicity Study

• Main Authors: Stéphanie Andrade (Author), Joana A. Loureiro (Author), Santiago Ramirez (Author), Celso S. G. Catumbela (Author), Claudio Soto (Author), Rodrigo Morales (Author), Maria Carmo Pereira (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liposomes are widely used as delivery systems for therapeutic purposes. However, the toxicity associated with the multi-dose administration of these nanoparticles is not fully elucidated. Here, we evaluated the toxicity of the prolonged administration of liposomes composed of neutral or cationic pho...