Antiproliferative Activity of a New Quinazolin-4(3<i>H</i>)-One Derivative via Targeting Aurora Kinase A in Non-Small Cell Lung Cancer

• Main Authors: Ji Yun Lee (Author), Huarong Yang (Author), Donghwa Kim (Author), Kay Zin Kyaw (Author), Ruoci Hu (Author), Yanhua Fan (Author), Sang Kook Lee (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-small cell lung cancer (NSCLC) is the most common lung cancer subtype. Although chemotherapy and targeted therapy are used for the treatment of patients with NSCLC, the survival rate remains very low. Recent findings suggested that aurora kinase A (AKA), a cell cycle regulator, is a potential ta...