Homologous recombination deficiency score is an independent prognostic factor in esophageal squamous cell carcinoma

• Главные авторы: Yulu Wang (Автор), Bowen Ding (Автор), Yunlan Tao (Автор), Lingli Huang (Автор), Qian Zhu (Автор), Chengying Gao (Автор), Mingli Feng (Автор), Yuchen Han (Автор)
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• Опубликовано: Wiley, 2024-11-01T00:00:00Z.
• Предметы: article
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Abstract Homologous recombination deficiency (HRD) represents an impairment in the homologous recombination repair (HRR) pathway, crucial for repairing DNA double‐strand breaks and contributing to genomic instability in cancer. The HRD score may be a more reliable biomarker than HRR‐related gene mut...