Homologous recombination deficiency score is an independent prognostic factor in esophageal squamous cell carcinoma

• Main Authors: Yulu Wang (Author), Bowen Ding (Author), Yunlan Tao (Author), Lingli Huang (Author), Qian Zhu (Author), Chengying Gao (Author), Mingli Feng (Author), Yuchen Han (Author)
• Format: Book
• Published: Wiley, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Homologous recombination deficiency (HRD) represents an impairment in the homologous recombination repair (HRR) pathway, crucial for repairing DNA double‐strand breaks and contributing to genomic instability in cancer. The HRD score may be a more reliable biomarker than HRR‐related gene mut...