Matrix Metalloproteinase-2 Inhibition in Acute Ischemia-Reperfusion Heart Injury-Cardioprotective Properties of Carvedilol

• Asıl Yazarlar: Monika Skrzypiec-Spring (Yazar), Joanna Urbaniak (Yazar), Agnieszka Sapa-Wojciechowska (Yazar), Jadwiga Pietkiewicz (Yazar), Alina Orda (Yazar), Bożena Karolko (Yazar), Regina Danielewicz (Yazar), Iwona Bil-Lula (Yazar), Mieczysław Woźniak (Yazar), Richard Schulz (Yazar), Adam Szeląg (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-12-01T00:00:00Z.
• Konular: article
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Matrix metalloproteinase 2 (MMP-2) is activated in hearts upon ischemia-reperfusion (IR) injury and cleaves sarcomeric proteins. It was shown that carvedilol and nebivolol reduced the activity of different MMPs. Hence, we hypothesized that they could reduce MMPs activation in myocytes, and therefore...