Artificial ovaries constructed from biodegradable chitin-based hydrogels with the ability to restore ovarian endocrine function and alleviate osteoporosis in ovariectomized mice

• Main Authors: Du Xiang (Author), Encheng Zhou (Author), Mei Wang (Author), Kan Wang (Author), Shujun Zhou (Author), Qing Ma (Author), Zibiao Zhong (Author), Qifa Ye (Author), Yun Chen (Author), Xiaoli Fan (Author), Yanfeng Wang (Author)
• Format: Bog
• Udgivet: BMC, 2023-05-01T00:00:00Z.
• Fag: article
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Abstract Background Artificial ovary (AO) is an alternative approach to provide physiological hormone to post-menopausal women. The therapeutic effects of AO constructed using alginate (ALG) hydrogels are limited by their low angiogenic potential, rigidity, and non-degradability. To address these li...