Deciphering the Mechanisms of Developmental Disorders (DMDD): a new programme for phenotyping embryonic lethal mice

• Main Authors: Timothy Mohun (Author), David J. Adams (Author), Richard Baldock (Author), Shoumo Bhattacharya (Author), Andrew J. Copp (Author), Myriam Hemberger (Author), Corinne Houart (Author), Matt E. Hurles (Author), Elizabeth Robertson (Author), James C. Smith (Author), Tom Weaver (Author), Wolfgang Weninger (Author)
• Format: Book
• Published: The Company of Biologists, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary International efforts to test gene function in the mouse by the systematic knockout of each gene are creating many lines in which embryonic development is compromised. These homozygous lethal mutants represent a potential treasure trove for the biomedical community. Developmental biologists...