Esculetin Inhibits Cancer Cell Glycolysis by Binding Tumor PGK2, GPD2, and GPI

• Main Authors: Song-Tao Wu (Author), Bo Liu (Author), Zhong-Zhu Ai (Author), Zong-Chao Hong (Author), Peng-Tao You (Author), He-Zhen Wu (Author), Yan-Fang Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glycolysis can improve the tolerance of tissue cells to hypoxia, and its intermediates provide raw materials for the synthesis and metabolism of the tumor cells. If it can inhibit the activity of glycolysis-related enzymes and control the energy metabolism of tumor, it can be targeted for the treatm...