Punicalagin Protects Human Retinal Pigment Epithelium Cells from Ultraviolet Radiation-Induced Oxidative Damage by Activating Nrf2/HO-1 Signaling Pathway and Reducing Apoptosis

• Автори: Maria Elisabetta Clementi (Автор), Beatrice Sampaolese (Автор), Francesca Sciandra (Автор), Giuseppe Tringali (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2020-06-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The oxidative damage of the retinal pigment epithelium (RPE) is the early event that underlies the pathogenesis of maculopathies. Numerous studies have shown that punicalagin (PUN), a polyphenol present in pomegranate, can protect several cell types from oxidative stress. Our study aims to establish...