SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging

• Main Authors: Yong Lan (Author), Min Dong (Author), Yongjun Li (Author), Yongpeng Diao (Author), Zuoguang Chen (Author), Yangfang Li (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Maintaining the health of the endothelium is of critical importance to prevention against cell aging. The current study was performed to clarify the role of sirtuin1 (SIRT1) in platelet phagocytosis in cell aging and identified its downstream molecular mechanism. Platelet phagocytosis by human endom...