Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation

• Main Authors: Chiara Sassoli (Author), Federica Pierucci (Author), Alessia Tani (Author), Alessia Frati (Author), Flaminia Chellini (Author), Francesca Matteini (Author), Ambra Vestri (Author), Giulia Anderloni (Author), Daniele Nosi (Author), Sandra Zecchi-Orlandini (Author), Elisabetta Meacci (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bone marrow-derived mesenchymal stromal cell- (BM-MSC-) based therapy is a promising option for regenerative medicine. An important role in the control of the processes influencing the BM-MSC therapeutic efficacy, namely, extracellular matrix remodelling and proliferation and secretion ability, is p...