RESISTANCE TO TARGETED THERAPIES IN MELANOMA: NEW INSIGHTS

Several molecular mechanisms are involved in melanoma genesis and progression. Molecular targets for effective therapeutic intervention have been identified within the RAS-RAF-MEK-ERK and, to a less extent, PI3K-AKT pathways. The development of inhibitors of key effectors (mainly BRAF mutant, MEK, a...

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Main Authors: Giuseppe Palmieri (Author), Maria Colombino (Author), Maria Cristina Sini (Author), Antonella Manca (Author), Paolo Antonio Ascierto (Author), Antonio Cossu (Author)
Format: Book
Published: European Medical Journal, 2013-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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