RESISTANCE TO TARGETED THERAPIES IN MELANOMA: NEW INSIGHTS
Several molecular mechanisms are involved in melanoma genesis and progression. Molecular targets for effective therapeutic intervention have been identified within the RAS-RAF-MEK-ERK and, to a less extent, PI3K-AKT pathways. The development of inhibitors of key effectors (mainly BRAF mutant, MEK, a...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
European Medical Journal,
2013-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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