Fisetin Inhibited Growth and Metastasis of Triple-Negative Breast Cancer by Reversing Epithelial-to-Mesenchymal Transition via PTEN/Akt/GSK3β Signal Pathway

• Main Authors: Jie Li (Author), Xia Gong (Author), Rong Jiang (Author), Dan Lin (Author), Tao Zhou (Author), Aijie Zhang (Author), Hongzhong Li (Author), Xiang Zhang (Author), Jingyuan Wan (Author), Ge Kuang (Author), Hongyuan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triple negative breast cancer (TNBC), characterized by its highly aggressive and metastatic features, is associated with poor prognosis and high mortality partly due to lack of effective treatment. Fisetin, a natural flavonoid compound, has been demonstrated to possess anti-cancer effects in various...