Efficacy and safety of hydroxychloroquine as pre-and post-exposure prophylaxis and treatment of COVID-19: A systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trials.

• Main Authors: Paulo Ricardo Martins-Filho, PhD (Author), Lis Campos Ferreira, MD, MSc (Author), Luana Heimfarth, PhD (Author), Adriano Antunes de Souza Araújo, PhD (Author), Lucindo José Quintans-Júnior, PhD (Author)
• Format: Book
• Published: Elsevier, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Background: Hydroxychloroquine (HCQ) is an anti-malarial and immunomodulatory drug considered a potential candidate for drug repurposing in COVID-19 due to their in vitro antiviral activity against SARS-CoV-2. Despite the potential antiviral effects and anti-inflammatory profile, the resul...