Ultra-deep sequencing of intra-host rabies virus populations during cross-species transmission.

• Main Authors: Monica K Borucki (Author), Haiyin Chen-Harris (Author), Victoria Lao (Author), Gilda Vanier (Author), Debra A Wadford (Author), Sharon Messenger (Author), Jonathan E Allen (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the hurdles to understanding the role of viral quasispecies in RNA virus cross-species transmission (CST) events is the need to analyze a densely sampled outbreak using deep sequencing in order to measure the amount of mutation occurring on a small time scale. In 2009, the California Departme...