Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma

• Main Authors: Jichun Han (Author), Dong Wang (Author), Lei Ye (Author), Peng Li (Author), Wenjin Hao (Author), Xiaoyu Chen (Author), Jun Ma (Author), Bo Wang (Author), Jing Shang (Author), Defang Li (Author), Qiusheng Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The cardiac ischemia-reperfusion (I/R) injury greatly influences the therapeutic effect and remains an urgent challenge in clinical therapy. Polypharmacology opens a new therapeutic opportunity to design drugs with a specific target for improving the efficacy. In this study, we first forecasted that...