Small molecules, inhibitors of DNA-PK, targeting DNA repair and beyond

• Main Authors: David eDavidson (Author), Lilian eAmrein (Author), Lawrence ePanasci (Author), Raquel eAloyz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Many current chemotherapies function by damaging genomic DNA in rapidly dividing cells ultimately leading to cell death. This therapeutic approach differentially targets cancer cells that generally display rapid cell division compared to normal tissue cells. However, although these treatments are in...