Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer

The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 binding to laminin is of high therapeutical in...

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Main Authors: Katharina Berg (Author), Tobias Lange (Author), Florian Mittelberger (Author), Udo Schumacher (Author), Ulrich Hahn (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available