Selection and Characterization of an α6β4 Integrin blocking DNA Aptamer
The heterodimeric laminin receptor α6β4 integrin plays a central role in the promotion of tumor cell growth, invasion, and organotropic metastasis. As an overproduction of the integrin is often linked to a poor prognosis, the inhibition of integrin α6β4 binding to laminin is of high therapeutical in...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2016-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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